Chris Collins

Tools · medical

Ultrasound, Doppler and dose numbers

Pulse-echo depth, wavelength, depth limit and frame rate; reflection at impedance boundaries; the Doppler shift and how an angle error moves the velocity; ultrasonic ranging in air; effective dose against natural background; Beer–Lambert, inverse square, and √N counting noise.

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How to use it

Educational — not a medical device. Not for diagnosis, treatment, monitoring or dosing. Effective dose is a population-level quantity for comparing procedures, not a measurement of harm to an individual, and the book’s notes on which test suits which question are orientation, not advice.

Companion to Chapter 16 (diagnostic devices) and Chapter 17 (treatment and life support) of Human Biology for the Medical Maker.

How to use it

Type into any box; results update. A value that is not a number, or is out of range, is reported rather than guessed at.

  • Pulse-echo — depth = c t / 2 at the assumed 1540 m/s (65 μs → 5 cm, the book’s example); wavelength λ = c / f (5 MHz → 0.3 mm); the depth limit from 0.5 dB/cm/MHz attenuation, counted both ways, over a 60 dB dynamic range (3 MHz → 20 cm, 10 MHz → 6 cm) with a plot of echo level against depth for several probe frequencies; and the frame rate when every line waits for the deepest echo (15 cm and 128 lines → about 40 frames per second).

  • Reflection — R = Z₂ − Z₁)/(Z₂ + Z₁² between any two materials in the impedance table, or your own Z values, with the transmitted fraction, the amplitude ratio (negative means the echo is inverted) and the echo level in dB. The book’s three boundaries — fat/muscle, soft tissue/bone, soft tissue/air — are checked against the table.

  • Doppler — Δf = 2 f₀ v cos θ / c (the book’s carotid example: 3.8 MHz, 0.88 m/s, 60° → 2.2 kHz), the velocity a machine reports from a measured shift, and the effect of entering the angle wrong: the change in cos θ and in the reported velocity, plotted against the true angle.

  • Air ranging — the chapter 16 exercise with a 40 kHz ultrasonic distance sensor: distance from the echo pulse width at 343 m/s (or from the air temperature), the echo time to expect for a distance, how far a fixed 343 m/s is off in cold or warm air, and the wavelength.

  • Dose — an effective dose in mSv as days of natural background, as a range because background is 2–3 mSv a year, with the book’s dose table on one log scale.

  • Attenuation and distance — I = I₀ e−μx with half- and tenth-value layers for water, cortical bone and lead at 60 and 100 keV, or your own μ; and the inverse-square law, D₂ = D₁ (d₁/d₂)².

  • Counting noise — a Monte Carlo of Poisson counting at means of 10 to 10⁴ (or your own list): the sample mean, standard deviation and mean/SD against √N, on a log–log plot, with a histogram of the smallest mean.

Links open a tab directly with the hash, for example #doppler, #echo, #reflect, #air, #dose, #atten or #count.

The ranging exercise is in air, on objects only. Never connect anything you built to a person.

Where the numbers come from

  • 1540 m/s, 0.5 dB/cm/MHz, 60 dB, the reflection and Doppler equations, the worked examples, the dose table and 2–3 mSv a year background, 343 m/s in air: Chapter 16 and Appendix C. Inverse square: Chapter 17.

  • Acoustic impedances (MRayl): air 0.0004, lung 0.18, fat 1.34, water 1.48, kidney 1.63, blood 1.65, liver 1.65, muscle 1.71, bone 7.8 — Radiopaedia, “Acoustic impedance”, after Bushberg et al., The Essential Physics of Medical Imaging. The book gives no Z values.

  • μ/ρ: NIST X-ray mass attenuation coefficients (Hubbell and Seltzer) — water 0.2059 and 0.1707, cortical bone (ICRU-44, 1.92 g/cm³) 0.3148 and 0.1855, lead (11.35 g/cm³) 5.021 and 5.549 cm²/g at 60 and 100 keV.

  • Speed of sound in dry air: c ≈ 331.3 √(1 + T/273.15) m/s (ideal gas, T in °C).

Limits

  • Straight-line physics: no beam spreading, focusing, refraction, speckle, nonlinear propagation or frequency-dependent speed of sound; attenuation is linear in frequency.

  • Reflection is for a flat boundary at normal incidence. Tissue impedances vary between sources and between people.

  • The Doppler tab assumes one velocity along one beam; real spectra spread, and aliasing limits the highest measurable shift.

  • Beer–Lambert values are narrow-beam and monoenergetic; a real X-ray spectrum hardens as it passes through material, and scatter adds to a broad beam.

  • Effective doses are typical adult values for comparison only. They vary widely with protocol, equipment and body size, and say nothing about any one person.

Related: CT and MRI lab (reconstruction, Hounsfield units, k-space, MRI), acoustics, decibels, isotope patterns, probability.

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